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. 2012 Oct 16;7(10):e47432. doi: 10.1371/journal.pone.0047432

Table 3. Comparing the local anaesthetic properties of 2-heptanone with the other ketones.

Substance3.41 mg/mL IT50 IT0 n
2-heptanone 39.14±4.84 221.88±7.32a 12
3-heptanone 40.82±1.67 258.00±11.47b 6
4-heptanone 45.24±0.44 283.57±16.89b 8
2-hexanone 74.42±0.79 401.00±33.20 7
2-octanone 81.45±1.58 555.00±75.00 4
3-octanone 117.10±0.53 722.50±95.66 6
2-pentanone 390.60±0.10 No measurable 6
3-pentanone 230.30±1.29 765.00±86.60 4
a,b

Significant difference (p<0.05) for the IT0 comparison between 2-heptanone, 3-heptanone and 4-heptanone.