Table 3. Comparing the local anaesthetic properties of 2-heptanone with the other ketones.
Substance3.41 mg/mL | IT50 | IT0 | n |
2-heptanone | 39.14±4.84 | 221.88±7.32a | 12 |
3-heptanone | 40.82±1.67 | 258.00±11.47b | 6 |
4-heptanone | 45.24±0.44 | 283.57±16.89b | 8 |
2-hexanone | 74.42±0.79 | 401.00±33.20 | 7 |
2-octanone | 81.45±1.58 | 555.00±75.00 | 4 |
3-octanone | 117.10±0.53 | 722.50±95.66 | 6 |
2-pentanone | 390.60±0.10 | No measurable | 6 |
3-pentanone | 230.30±1.29 | 765.00±86.60 | 4 |
Significant difference (p<0.05) for the IT0 comparison between 2-heptanone, 3-heptanone and 4-heptanone.