Skip to main content
. 2012 Oct 16;7(10):e47409. doi: 10.1371/journal.pone.0047409

Table 1. Measuring the effects of BART miRNAs on expression levels of cellular proteins using 2D DIGE.

Spot Protein NCBI AccessionNumber Gene Fold change of protein (BJAB BARTs/BJAB Empty)
1 Heat shock 70 kDa protein 5 GI: 16507237 HSPA5 −1.31
2 Heat shock 90 kDa protein 1, beta GI: 20149594 HSP90AB1 −1.45
3 Heat shock 70 kDa protein 9 precursor GI: 24234688 HSPA9 −1.38
5;6 Gelsolin isoform b GI: 38044288 GSN −1.48; −1.40
6;7 Ezrin GI: 46249758 EZR −1.60; 1.31
8 Synaptotagmin binding, cytoplasmic RNA interacting protein,isoform CRA_e GI: 119569012 SYNCRIP 1.33
9 Calreticulin precursor variant GI: 62897681 CALR 1.65
10 Heat shock protein 60 GI: 77702086 HSPD1 1.47
11 Protein disulfide-isomerase A3 precursor GI: 21361657 PDIA3 1.62
12 T-complex protein1 isoform a GI: 57863257 TCP1 1.33
13 Nucleosome assembly protein 1-like 1 GI: 4758756 NAP1L1 2.00
14; 15; 16 ACTB protein GI: 15277503 ACTB 1.44; −2.14; −1.87
17 Annexin VII isoform 1 GI: 4502111 ANXA7 −1.49
18 Alpha-enolase isoform 1 GI: 4503571 ENO1 −1.40
19 SET GI: 145843637 SET1 −1.89
20 Nudix (nucleoside diphosphate linked moiety X)-type motif 5,isoform CRA_a* GI: 119606726 NUDT5 −1.31
21 Serine/arginine-rich splicing factor 1 isoform 1 GI: 5902076 SFRS1 −1.37
22 Inorganic pyrophosphatase GI: 11056044 PPA1 −1.36
23 Bisphosphoglycerate mutase GI: 4502445 BPGM −1.32
24 Phosphoglycerate mutase 1 (brain) GI: 38566176 PGAM1 −1.51
25 Glutathione S-transferase GI: 2204207 GSTP1 −1.42
26 Peroxiredoxin-1 GI: 4505591 PRDX1 −2.03
27; 28 Cellular nucleic acid-binding proteinisoform 1 GI: 187608726 CNBP1 −1.35; −1.32
29 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialisoform 2 GI: 4503423 DUT −1.30
30 Hypothetical protein LOC51237* GI: 117938314 MZB1 −1.57
31 Eukaryotic translation initiation factor 5A-1 isoform B GI: 4503545 EIF5A −2.10
32 Cofilin-1 GI: 5031635 CFL1 −1.35
33 60S acidic ribosomal protein P2 GI: 4506671 RPLP2 −2.08
34 Fatty acid-binding protein, epidermal GI: 4557581 FABP5 −1.49
35 ISG15 ubiquitin-like modifier GI: 14550514 ISG15 −1.48
*

Not characterized as a protein.

Full list of candidates identified as being regulated by the BART miRNAs via 2D DIGE, along with changes in the protein levels observed in the presence of the miRNAs is shown.