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. 2012 Oct 16;7(10):e46973. doi: 10.1371/journal.pone.0046973

Figure 1. Ox-LDL stimulates cell proliferation and expression of scavenger receptors.

Figure 1

(A) – For evaluation of proliferative response to ox-LDL measured by cell count and MTT assay, MCF10A cells were exposed to different concentrations of ox-LDL (1–100 µg/ml) for 24 hours; (B) – uptake of Dyl-ox-LDL by MCF10 A cells was visualized by fluorescent microscopy after 2 hours of incubation with 1 µg/ml Dil-ox-LDL; (C) – Western blot for scavenger receptors and (D) – graph depicting relative densities of bands normalized for β-actin in relation to control (fold change). (*) – significant difference (p<0.05) compared to control. For these experiments, MCF10A cells were treated with 20 µg/ml ox-LDL for 2 and 12 hours.