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. 2012 Oct 16;7(10):e46916. doi: 10.1371/journal.pone.0046916

Table 2. Salivary IgG antibody levels (GMC; ng/ml) in children after 2 doses, 2+1-doses of PCV7 or no PCV7 vaccinations (controls) at the age of 12 and 24 months.

12 months 24 months
Controls 2-dose 2+1-dose Controls 2-dose 2+1-dose
Serotype n = 60 n = 54 n = 63 p-Values n = 55 n = 58 n = 62 p-Values
4 1.8 11.3 124.0 α, β, γ 1.5 6.0 14.8 α, β, γ
6B 4.4 12.7 188.2 α, β, γ 7.1 40.4 67.0 β, γ
9V 2.6 18.7 177.9 α, β, γ 2.7 11.8 34.3 α, β, γ
14 3.1 49.7 360.3 α, β, γ 3.2 15.7 52.3 α, β, γ
18C 1.1 11.5 137.3 α, β, γ 2.0 8.8 19.0 α, β, γ
19F 11.2 33.8 147.2 α, β, γ 19.7 72.3 85.7 β, γ
23F 1.2 8.2 112.4 α, β, γ 2.0 12.8 39.7 α, β, γ
1 4.6 3.0 3.7 4.3 4.1 5.7
3 1.2 1.3 0.7 1.0 1.4 1.5
5 8.6 7.3 9.1 11.2 10.7 12.9
7F 5.1 3.3 3.5 4.2 3.1 5.3

α p-Values<0.05; 2+1 vs. 2-dose schedule.

β p-Values<0.05; 2+1-dose vs. controls.

γ p-Values<0.05; 2-dose vs. controls.

Calculated using log transformed unpaired t test, p-values are 2 sided.