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. 2012 Oct 16;7(10):e46916. doi: 10.1371/journal.pone.0046916

Table 3. Salivary IgA antibody levels (GMC; ng/ml) in children after 2 doses, 2+1-doses of PCV7 or no PCV7 vaccinations (controls) at the age of 12 and 24 months.

12 months 24 months
Controls 2-dose 2+1-dose Controls 2-dose 2+1-dose
Serotype n = 57 n = 51 n = 58 p-Values n = 49 n = 50 n = 59 p-Values
4 2.5 4.3 8.2 α, β, γ 3.2 3.8 4.9 β
6B 1.4 2.9 18.4 α, β, γ 5.1 14.2 22.0 β, γ
9V 2.4 4.1 10.3 α, β, γ 4.9 4.2 11.8 α, β
14 2.5 17.5 78.3 α, β, γ 9.5 15.6 26.6 β
18C 0.8 0.9 3.6 α, β 2.4 1.5 3.3 α
19F 7.2 10.0 11.8 18.6 31.0 32.0
23F 1.0 1.6 9.6 α, β 2.5 4.2 9.2 β
1 4.4 3.9 3.1 4.8 4.0 4.2
3 8.6 12.0 8.3 9.7 11.9 14.9
5 4.8 4.1 4.3 6.2 5.2 6.8
7F 4.7 3.7 3.4 6.4 4.8 6.3

α p-Values<0.05; 2+1 vs. 2-dose schedule.

β p-Values<0.05; 2+1-dose vs. controls.

γ p-Values<0.05; 2-dose vs. controls.

Calculated using log transformed unpaired t test, p-values are 2 sided.