Table 3. Salivary IgA antibody levels (GMC; ng/ml) in children after 2 doses, 2+1-doses of PCV7 or no PCV7 vaccinations (controls) at the age of 12 and 24 months.
12 months | 24 months | |||||||
Controls | 2-dose | 2+1-dose | Controls | 2-dose | 2+1-dose | |||
Serotype | n = 57 | n = 51 | n = 58 | p-Values | n = 49 | n = 50 | n = 59 | p-Values |
4 | 2.5 | 4.3 | 8.2 | α, β, γ | 3.2 | 3.8 | 4.9 | β |
6B | 1.4 | 2.9 | 18.4 | α, β, γ | 5.1 | 14.2 | 22.0 | β, γ |
9V | 2.4 | 4.1 | 10.3 | α, β, γ | 4.9 | 4.2 | 11.8 | α, β |
14 | 2.5 | 17.5 | 78.3 | α, β, γ | 9.5 | 15.6 | 26.6 | β |
18C | 0.8 | 0.9 | 3.6 | α, β | 2.4 | 1.5 | 3.3 | α |
19F | 7.2 | 10.0 | 11.8 | 18.6 | 31.0 | 32.0 | ||
23F | 1.0 | 1.6 | 9.6 | α, β | 2.5 | 4.2 | 9.2 | β |
1 | 4.4 | 3.9 | 3.1 | 4.8 | 4.0 | 4.2 | ||
3 | 8.6 | 12.0 | 8.3 | 9.7 | 11.9 | 14.9 | ||
5 | 4.8 | 4.1 | 4.3 | 6.2 | 5.2 | 6.8 | ||
7F | 4.7 | 3.7 | 3.4 | 6.4 | 4.8 | 6.3 |
α p-Values<0.05; 2+1 vs. 2-dose schedule.
β p-Values<0.05; 2+1-dose vs. controls.
γ p-Values<0.05; 2-dose vs. controls.
Calculated using log transformed unpaired t test, p-values are 2 sided.