Table 3.
Stepwise multivariate linear regression associations with plasma Aβ40 and Aβ42
| Variable | Parameter (β) | Standard Error | F-value | p-value |
|---|---|---|---|---|
| Aβ40 | ||||
| Age | 1.34 | 0.53 | 6.39 | 0.01 |
| Black race | −14.70 | 3.13 | 22.01 | <0.0001 |
| Creatinine | 52.91 | 4.29 | 151.77 | <0.0001 |
| Serum BDNF | −0.0004 | 0.0001 | 7.34 | 0.007 |
|
| ||||
| Aβ42 | ||||
| Black race | −3.72 | 0.67 | 30.83 | <0.0001 |
| Femal sex | 1.39 | 0.67 | 4.32 | 0.04 |
| Education | 1.50 | 0.69 | 4.78 | 0.03 |
| APOE e4 | −2.82 | 0.69 | 16.57 | <0.0001 |
| Creatinine | 9.32 | 0.85 | 120.09 | <0.0001 |
Aβ40 indicates amyloid beta-40; Aβ42 amyloid beta-42; BDNF brain-derived neurotrophic factor; APOE Apolipoprotein E.