Table 1. Timeline of Chronic Drug or Vehicle Treatment and the Months in which Physiological Development, Cytogenetic, Cognitive-Behavioral (SSRT, DE/MP, ID/ED, and/or ORD tasks), and PET Assessments were Conducted.
| Assessment | Baseline | 6-Month treatment | Break | 12-Month treatment | Post-treatment | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Month in study | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 |
| Cumulative months of treatment | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | |||||||||
| Physiol. develop. | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
| Cytogenetic | X | X | X | X | X | X | |||||||||||||||||||||
| Activity | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
| SSRT | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
| DE/MP | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
| ID/ED | X | X | X | X | |||||||||||||||||||||||
| ORD | X | X | X | ||||||||||||||||||||||||
| PET | X | X | X | X | |||||||||||||||||||||||
General activity level was collected continuously throughout all conditions. Each block in the body of the table represents 1 month.