Table 1. Epidemiology and demographics of small intestine neoplasms.
Histology | Incidence per year | m/f ratio | Risk factors | 5 year survival rate |
Adenocarcinoma | Overall = 0.4 per 100 000 | W m/f = 1.5 | Crohn disease, | 26.6–39% |
Wm = 30.8% | B m/f = 1.2 | coeliac disease, | ||
Wf = 32.7% | familiary adenomatous | |||
Bm = 37.2% | polyposis, | |||
Bf = 45.5% | Meckel diverticulum | |||
Carcinoid | Overall = 0.4 per 100 000 | W m/f = 1.4 | MEN1 | 60–76.5% |
Wm = 36.0% | B m/f = 1.6 | |||
Wf = 39.2% | ||||
Bm = 43.9% | ||||
Bf = 39.7% | ||||
Lymphoma | Overall = 0.3 per 100 000 | W m/f = 1.9 | EBV, AIDS (B cell) | 8–25% |
Wm = 22.9% | B m/f = 2.3 | Coeliac disease (T cell) | ||
Bm = 11.4% | Chemotherapy | |||
Wf = 17.9% | ||||
Bf = 7.3% | ||||
GIST | Overall = 0.2 per 100 000 | W m/f = 1.4 | No | 45–55% |
Wm = 10.3% | B m/f = 1.4 | |||
Bm = 7.4% | ||||
Wf = 10.2% | ||||
Bf = 7.5% | ||||
Metastases | Autopsy series: | Lung cancer | End stage of disease, resection of solitary lesions may prolong survival | |
Lung cancer (12%) | Melanoma | |||
Breast cancer (16%) | Breast cancer | |||
Melanoma (42%) |
W, white; B, black; m, male; f, female; EBV, Epstein-Barr virus; AIDS, acquired immune deficiency syndrome; GIST, gastrointestinal stromal tumour.