Table 6. Treatment options and outcome in relation to tumour stage for patients with a squamous cell carcinoma of oral cavity, oropharynx, hypopharynx and larynx.
n | TRT option | St I | St II | St III | St IV | Recurrence (recurr)/progression (progr) | n death/cause |
Definitive IMRT (30 patients) | |||||||
17 | RT | 4a | 9b | 4cde | 0 | 2 Tu recurrab, 1 LN recurrc | 1 LN recurrc, 1 postop complicationd |
8 | CRT | 0 | 3fgh | 1i | 4jkl | 1 Tu recurrf, 1 Tu and LN recurrg, 1 Tu progrj | 1 Tu progrj, 2 × 2nd primaryhk, 1 toxic deathl |
5 | ICT→CRT | 0 | 1m | 0 | 4no | 1 Tu recurrm, 2 Tu progrno | 1 Tu recurrm, 1 Tu progrn, 1 Tu progr & M+o |
Post-operative IMRT (18 patients) | |||||||
13 | RT | 2 | 4 | 4p | 3q | 1 LN recurrp, 1 Tu & LN recurrq | |
5 | CRT | 0 | 1 | 0 | 4r | 1 Tu recurrr | 1 Tu recurrr |
TRT, treatment; postop, post-operative; CRT, concurrent chemotherapy and IMRT; ICT, induction chemotherapy; RT, radiotherapy; IMRT, intensity modulated radiotherapy; St, stage; M+, metastasis; d,e,f,i, salvage surgery; Tu, primary tumour; LN, lymph node.