Figure 5.

The optimised dose in the cerebellum (thick solid line) and outside the hippocampus +5 mm and cerebellar regions (dashed line) is shown as a function of the average dose outside of the hippocampus +5 mm region. The best estimate for the prevalence of metastases in the hippocampus +5 mm region (0.0072) and the best estimate for the prevalence of metastases in the cerebellum (0.256) were used. The estimates for prevalence in the different regions are based on the data for lung cancer (small cell lung cancer and non-small cell) and maximal reseeding is considered. A line representing a uniform whole brain dose is drawn for reference (thin solid line).