Figure 1.

Effect of melatonin pre-treatment (100 μg/100 g body weight) on total leukocyte count (TLC) of Funambulus pennanti following exposure to 5 Gy γ-radiation. Animals were sacrificed after 4, 24, 48, 72 and 168 h during (a) the reproductively active phase (RAP, May) and (b) the reproductively inactive phase (RIP, December). (c) A comparison of TLC between RAP and RIP in irradiated (I) and melatonin-treated plus irradiated (MI) groups, in which controls of both phases were assumed to be 100%, was completed. Vertical bars represent mean±SEM (standard error of the mean), n _ 5 for each group. The statistical significance is indicated: a _ p<0.05 and b _ p<0.01 when compared with the control group; c _ p<0.05 and d _ p<0.01 when compared with the irradiated group. Con, control; Mel, melatonin only; Irrd, irradiation only; Mel+Irrd, melatonin treatment and irradiation.