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CT scan images in a patient with limited (pT2pN0M0) disease; there is significant difference in the size of the tumour on (a) the lung and (b) mediastinal CT scan windows. The modified tumour shadow disappearance rate (mTDR) was 0.59. In contrast, in another patient with advanced disease (pT2pN0M1: vertebral metastases) there is minimal difference in tumour size between (c) the lung and (d) mediastinal windows. mTDR was 0.04.
