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Epidermal spongiosis scores in (a) high dose broad-beam (BB) and (b) low dose BB and microbeam radiotherapy-irradiated mouse skin tissue for different doses and times. Error bars are standard error of the mean (SEM). (c) Spongiosis involving only the bottom third of the epidermis layer. (d) Spongiosis with intra-epidermal vesicles.
