Table 3. Association between types of lesions on sonograms and prognostic factors.
Type of lesion on sonogram and prognostic factor | Number (%) | OR | 95% CI | p-value |
Extensive intraductal component | <0.001* | |||
Oval masses without calcifications | 49/280 (18) | Reference | NA | |
Oval masses with calcifications | 23/48 (48) | 4.34 | 2.28, 8.26 | <0.001* |
Irregular masses without calcifications | 59/260 (23) | 1.38 | 0.91, 2.11 | 0.133 |
Irregular masses with calcifications | 66/119 (55) | 5.87 | 3.65, 9.44 | <0.001* |
Calcifications alone | 7/8 (88) | 33.00 | 3.97, 274.34 | 0.001* |
Positive HER-2/neu status | <0.001* | |||
Oval masses without calcifications | 45/280 (16) | Reference | NA | |
Oval masses with calcifications | 22/48 (46) | 4.42 | 2.30, 8.48 | <0.001* |
Irregular masses without calcifications | 50/260 (19) | 1.24 | 0.80, 1.94 | 0.336 |
Irregular masses with calcifications | 46/119 (39) | 3.29 | 2.02, 5.36 | <0.001* |
Calcifications alone | 2/8 (25) | 1.74 | 0.34, 8.90 | 0.506 |
NA, not applicable; OR, odds ratio.
*These were considered to be statistically significant parameters.
Note – Logistic regression analysis was used to evaluate the ORs of the sonographic types for a specific prognostic factor. For the explanatory variables, we have chosen “oval masses without calcifications” as the reference for the other sonographic types in order to determine ORs that predict a specific prognostic factor.