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50-year-old female with multifocal bronchoalveolar carcinoma on single agent erlotinib for 5 months. Axial contrast-enhanced routine staging CT abdomen demonstrates pneumatosis of the wall of the fluid-filled right colon (arrow). CT abdomen performed 2 weeks later while patient remained off erlotinib (not shown) revealed complete resolution of pneumatosis, with normal colonic stool. Erlotinib was discontinued permanently.
