Table 4. Diagnostic performance of contrast-enhanced ultrasound in discriminating hepatocellular carcinomas from non-neoplastic lesions in terms of nodules size.

Parameter	Nodule diameter
	1.0–2.0 cm (n=65)	2.1–3.0 cm (n=37)	3.1–5.0 cm (n=45)
Sensitivity	69.2% (27/39)a,b	97.1% (33/34)a	100.0% (43/43)b
Specificity	100.0% (26/26)	100.0% (3/3)	100.0% (2/2)
PPV	100.0% (27/27)	100.0% (33/33)	100.0% (43/43)
NPV	68.4% (26/38)	75.0% (3/4)	100.0% (2/2)
Accuracy	81.5% (53/65)c,d	97.3% (36/37)c	100.0% (45/45)d

NPV, negative predictive value; PPV, positive predictive value.

The values with the same superscript are compared:

^ap=0.002.

^bp<0.001.

^cp=0.002.

^dp=0.001.