Table 3. Distribution of morphological features in benign and malignant focal ground-glass opacity on mutidetector CT.
fGGO | Benign (n=21) |
Malignant (n=61) |
p-value | ||||
mGGO | pGGO | Total 1 | mGGO | pGGO | Total 2 | ||
Shape | |||||||
Irregularity | 10 | 1 | 11 (52.4) | 13 | 0 | 13 (21.3) | 0.07a |
Round/oval | 4 | 6 | 10 (47.6) | 41 | 7 | 48 (78.7) | |
Margin | |||||||
Lobulation | 2 | 1 | 3 (14.3) | 48 | 3 | 51 (83.6) | 0.000a |
Spiculation | 1 | 0 | 1 (4.8) | 21 | 0 | 21 (34.4) | 0.008a |
Cusp angle | 2 | 0 | 2 (9.5) | 2 | 0 | 2 (3.3) | 0.568b |
Spine-like process | 0 | 0 | 0 (0) | 18 | 0 | 18 (29.5) | 0.004b |
Interface | |||||||
Ill defined | 9 | 5 | 14 (66.7) | 1 | 0 | 1 (1.6) | 0.000b |
Well defined, smooth | 0 | 0 | 0 (0) | 0 | 3 | 3 (4.9) | 0.566b |
Well defined, coarse | 5 | 2 | 7 (33.3) | 53 | 4 | 57 (93.4) | 0.000b |
Internal characteristics | |||||||
Air bronchograms | |||||||
Natural | 3 | 2 | 5 (23.8) | 9 | 0 | 9 (14.8) | 0.502b |
Dilated and distorted | 3 | 0 | 3 (14.3) | 9 | 0 | 9 (14.8) | 1.000b |
Cut-off | 0 | 0 | 0 (0) | 19 | 1 | 20 (32.8) | 0.003a |
Air-containing space | 3 | 0 | 3 (14.3) | 33 | 3 | 36 (59.0) | 0.000a |
Adjacent structure | |||||||
Pleural indentation | 1 | 0 | 1 (4.8) | 40 | 3 | 43 (70.5) | 0.000a |
Vascular convergence | 1 | 0 | 1 (4.8) | 22 | 0 | 22 (36.1) | 0.006a |
fGGO, focal ground-glass opacity; mGGO, mixed ground-glass opacity; pGGO, pure ground-glass opacity.
Data are expressed in terms of frequency or percentages (in parentheses).
aχ2 test.
bFisher's exact test.