Table 1. Summary of the most common pancreatic neuroendocrine neoplasms.

Tumour	Symptoms and clinical findings	Primary location	Malignant (%)
Insulinoma	Hypoglycaemia, neuroglycopenic symptoms	Pancreas (equally throughout)	5–15
Gastrinoma	Abdominal pain, diarrhoea, peptic ulcers	Gastrinoma triangle	>50
Glucagonoma	Necrolytic migratory erythema, hyperglycaemia, venous thrombosis, weight loss	Pancreas (tail)	>60
VIPoma	Watery diarrhoea, hypokalaemia, achlorhydria (WDHA syndrome)	Pancreas (tail>head, body); rarely adrenal and periganglionic tissue	>50
Somatostatinoma	Hyperglycaemia, cholelithiasis, diarrhoea, steatorrhoea	Pancreas, duodenum	>60
Non-functioning tumours	Abdominal pain, weight loss	Pancreas (head>body, tail)	60–90

VIPoma, vasoactive intestinal peptide tumours.