Table 1.
Demographics and clinical measuresa.
| Characteristic | HC (n = 20)f | SZ (n = 20) | t/χ2 | p-value |
|---|---|---|---|---|
| Age, years | 36.3 ± 11.3 | 39.0 ± 11.4 | 0.75 | 0.46 |
| Gender, F/M | 8/12 | 9/11 | 0.10 | 0.75 |
| Ethnicity, AA/Cb | 10/10 | 14/6 | 0.94 | 0.33 |
| Parental SESc | 6.7 ± 5.1 | 6.8 ± 5.0 | 0.07 | 0.94 |
| RBANSd | ||||
| Total index | 87.2 ± 12.5 | 73.7 ± 10.2 | 6.16 | 0.002 |
| Immediate memory | 88.6 ± 15.3 | 77.5 ± 12.3 | 6.43 | 0.03 |
| Visuospatial | 79.9 ± 15.7 | 79.9 ± 15.7 | 2.31 | 0.69 |
| Language | 95.5 ± 14.4 | 87.3 ± 13.7 | 2.95 | 0.11 |
| Attention | 96.4 ± 20.8 | 82.3 ± 12.9 | 4.58 | 0.03 |
| Delayed memory | 91.8 ± 8.4 | 72.5 ± 20.7 | 5.38 | 0.001 |
| BPRSe | ||||
| Total | – | 29.2 ± 6.8 | – | – |
| Positive | – | 4.5 ± 2.6 | – | – |
| Negative | – | 4.3 ± 2.0 | – | – |
χ2 includes Yate’s correction.
aMean ± SD unless indicated otherwise; SZ, schizophrenia; HC, healthy control.
bAA, African American; C, Caucasian.
cSocioeconomic Status; Ranks determined from Diagnostic Interview for Genetic Studies (1–18 scale); higher rank (lower numerical value) corresponds to higher socioeconomic status; information not available for one SZ.
dRepeatable Battery for the Assessment of Neuropsychological Status; data not available for two SZ and two HC.
eBrief Psychiatric Rating Scale (1–7 scale); positive (conceptual disorganization, hallucinatory behavior, and unusual thought content); negative (emotional withdrawal, motor retardation, and blunted affect); data not available for two SZ.
f18 SZ were treated with second generation antipsychotics and two SZ were not taking antipsychotics.