Table 2.
(A) List of miRNAs that were validated on TaqMan® qRT-PCR. The right column shows the p-values for the comparison of between versus malignant and the line is drawn to divide the statistically significant and unsignificant miRNAs. P-value was calculated using Mann-Whitney U test. 15 out of 25 miRNAs were statistically significant. miR-32* value is not shown here as it did not amplify on TaqMan qRT-PCR®. (B) Area under the curve (AUC) values were calculated for the miRNAs that were statistically significant based on the Mann-Whiteney U test. The line is drawn to divide the statistically significant and unsignificant miRNAs.
miRNA | p-value |
---|---|
| |
hsa-miR-7 | 0.0004 |
hsa-miR-126 | 0.0018 |
hsa-miR-374a | 0.0027 |
hsa-let-7g | 0.0027 |
hsa-miR-30c | 0.0058 |
hsa-miR-195 | 0.0075 |
hsa-miR-335 | 0.009 |
hsa-miR-30b | 0.0139 |
hsa-miR-451 | 0.0165 |
hsa-miR-145 | 0.0197 |
hsa-miR-193a-3p | 0.0197 |
hsa-miR-22 | 0.0247 |
hsa-miR-144 | 0.0326 |
hsa-miR-143 | 0.04 |
hsa-miR-101 | 0.0466 |
| |
hsa-miR-30a | 0.0597 |
hsa-miR-26b | 0.0657 |
hsa-miR-744 | 0.0831 |
hsa-miR-146b-5p | 0.1517 |
hsa-let-7f | 0.1643 |
hsa-miR-30e | 0.1709 |
hsa-miR-222 | 0.2226 |
hsa-miR-221 | 0.2479 |
hsa-miR-30b* | 0.5634 |
| |
A. |
miRNA | AUC value |
---|---|
| |
hsa-miR-7 | 0.806 |
hsa-miR-126 | 0.767 |
hsa-miR-374a | 0.756 |
hsa-let-7g | 0.756 |
hsa-miR-30c | 0.736 |
hsa-miR-195 | 0.729 |
hsa-miR-335 | 0.723 |
hsa-miR-30b | 0.711 |
hsa-miR-451 | 0.705 |
| |
hsa-miR-145 | 0.7 |
hsa-miR-193a-3p | 0.7 |
hsa-miR-22 | 0.692 |
hsa-miR-144 | 0.688 |
hsa-miR-143 | 0.676 |
hsa-miR-101 | 0.67 |
| |
B. |