Figure 4.

The effects of pretest injection of saffron extract on time latency for entering the dark compartment. The animals of the control group received saline instead of both saffron extract and morphine. The animals of morphine group were treated by saline instead of SE but received morphine (5 mg/kg, s.c.) 30 min before the training phase. Pretest 150 and pretest 450 groups were treated by 150 and 450 mg/kg of SE (i.p.), respectively, before the recall phase. The data were presented as mean ± SEM of the time latency (8 animals in each group). **P < 0.01 compared with the control group and ⁺⁺ P < 0.01 compared with the morphine group.