Table 10. Ames Test Results.
compd | dose (μg/plate) | no. of revertants without S9 | no. of revertants in the presence of S9 |
---|---|---|---|
3 | 15 | 5.5 ± 2.5 | 8.0 ± 0.5 |
5 | 9.5 ± 0.5 | 6.0 ± 1.0 | |
1.6 | 8.5 ± 0.5 | 9.0 ± 0.5 | |
0.5 | 9.5 ± 0.5 | 9.0 ± 2.0 | |
0.18 | 9.0 ± 1.0 | 9.0 ± 0.5 | |
7 | 20 | 8.5 ± 0.5 | 10.0 ± 0.5 |
6 | 8.0 ± 0.5 | 9.0 ± 1.0 | |
2 | 11.5 ± 1.5 | 13.0 ± 2.0 | |
0.7 | 12.0 ± 1.0 | 12.5 ± 3.5 | |
0.2 | 12.0 ± 3.0 | 10.5 ± 0.5 | |
9 | 20 | 4.0 ± 0.5 | 9.5 ± 3.5 |
6.7 | 10.5 ± 2.0 | 14.5 ± 0.5 | |
2.2 | 7.5 ± 2.0 | 6.5 ± 0.5 | |
0.7 | 13.0 ± 9.0 | 8.5 ± 0.5 | |
0.27 | 8.5 ± 1.5 | 7.5 ± 1.5 | |
14 | 20 | (a) | 5.0 ± 1.0 |
6.7 | 9.5 ± 0.5 | 7.0 ± 0.5 | |
2.2 | 9.5 ± 3.0 | 7.0 ± 0.5 | |
0.7 | 2.5 ± 0.5 | 7.0 ± 3.0 | |
0.27 | 8.0 ± 1.0 | 7.5 ± 0.5 | |
15 | 20 | 6.0 ± 3.0 | 11.5 ± 2.0 |
6.7 | 25.0 ± 20.0 | 6.0 ± 0.5 | |
2.2 | 8.0 ± 1.5 | 9.0 ± 2.0 | |
0.7 | 10.5 ± 2.0 | 10.5 ± 0.5 | |
0.27 | 8.0 ± 4.0 | 9.5 ± 2.5 | |
control (−) PBS | – | 11.5 ± 2.5 | |
control (+) NPDb | – | 852 | – |
control (−) S9 | – | – | 9.5 ± 1.5 |
control (+) 2AFc | – | – | 412 |
Some toxicity was observed that did not allow us to evaluate the revertants.
NPD (2-nitro-o-phenylendiamine).
2AF (2-aminofluorene).