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. Author manuscript; available in PMC: 2012 Oct 17.
Published in final edited form as: Tissue Antigens. 2010 Mar 1;76(1):31–34. doi: 10.1111/j.1399-0039.2010.01460.x

Table 2.

Novel KIR2DL1 alleles observed in African Americans

KIR2DL1
Novel Allele		 Most Similar
Allele		 Alteration
Nucleotide Codon (Amino Acid)a 		Protein Region
Altered		 GenBank
Accession
Number		 Cell Line
2DL1*00403 2DL1*00401 254 GCG (A ) => GCT (A) -- EU930369 GM17109
2DL1*01101 2DL1*00401 -17 GTC (V) => TTC (F), 221 CGA (R) => AGA (R) Signal peptide EU930368 GM17159
2DL1*01102 2DL1*00401 -17 GTC (V) => TTC (F), 186 TAC (Y) => TAT (Y) Signal peptide FJ655851 GM17200 b
2DL1*012 2DL1*001 16 CCC (P) => CGC (R) Domain 1 EU930370 GM17119b
2DL1*013N 2DL1*00401 -17 GTC (V) => TTC (F), 35 GAA (E) => TAA (Stop) Truncated EU930371 GM17120
2DL1*014 2DL1*00302 179 GGC (G) => AGC (S) Domain 2 EU930372 GM17123 b
2DL1*015 2DL1*00302 275 GAC (D) => GAA (E) Cytoplasmic EU930373 GM17124
2DL1*016 2DL1*00303 296 CGC (R) => TGC (C) Cytoplasmic FJ655852 GM17126
2DL1*017 2DL1*00302 221 CGA (R) => CAA (Q) Transmembrane FJ655853 GM17131
2DL1*018 2DL1*00302 282 ACA (T) => CCA (P) Cytoplasmic FJ655854 GM17153
2DL1*019 2DL1*00303 114 CTG (L) => CCG (P), 226 CTG (L) => GTG (V) Domain 2
Transmembrane		 FJ655855 GM17160 b
a

Most similar known allele => novel allele

b

This allele was found in more than one individual: KIR2DL1*01102, GM17198; KIR2DL1*012, GM17141, GM17142, GM17166, GM17185; KIR2DL1*014, GM17140, GM17174; KIR2LD1*019, GM17102.