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. 2012 Oct 17;3:369. doi: 10.3389/fmicb.2012.00369

Figure 2.

Figure 2

Mapping of CA functional domains and two major protective CTL alleles. Gray boxes show β-hairpin (amino acids 4–14) or helix structures (H1–H11). Thick black bars indicate the CTL epitopes restricted by each allele (Llano et al., 2009). The NTD-NTD, CTD-NTD, or hexamer-hexamer/pentamer interacting regions are indicated. Three amino residues (N74, A105, and R132), which are reported to change CypA dependency, are shown in circles (Schneidewind et al., 2007; Yang and Aiken, 2007; Ambrose et al., 2012). The reference amino acids sequences are from HXB2 (accession number; AB50258.1).