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. Author manuscript; available in PMC: 2013 Sep 27.
Published in final edited form as: J Med Chem. 2012 Sep 18;55(18):7998–8006. doi: 10.1021/jm300804e

Figure 3.

Figure 3

Protection of RAW264.7 and HT1080 cells by small molecule toxin inhibitors. RAW264.7 cells were exposed to 0.9 nM PA with 5.6 nM LF (A) or 0.06 nM PA with 1.88 nM FP59 (B) and HT1080 cells were exposed to 0.6 nM PA (C) or PA-L1 (D) with 1.88 nM FP59 for 5 h. The PA + LF cells were stained with MTT immediately (A) while the PA + FP59 and PA-L1 + FP59 cells (B-D) were treated with 10 mM ammonium chloride after 5 h to stop intoxication and MTT stained 48 h later. Data are plotted as mean +/- standard error of four independent experiments. Percent survival is compared to a non-intoxicated control.