Table 3.

Management guidelines for patients with nonalcoholic fatty liver disease.

Consider screening for type 2 diabetes mellitus (T2DM) and cardiovascular disease Lifestyle interventions (weight loss; exercise) Treatment of dyslipidemia: — Statin therapy with close monitoring of liver function tests — Consider combination therapy versus high triglycerides and low high-density lipoprotein cholesterol Treatment of T2DM: achieve good glycemic control — Metformin (first-line therapy) — Consider earlier use of pioglitazone Treatment of nonalcoholic steatohepatitis — In nondiabetics: consider vitamin E — In T2DM: consider pioglitazone