Fig. 2.

Sex differences in estradiol stimulated progesterone synthesis in post-pubertal hypothalamic astrocytes. Estradiol at 1 nM and 100 nM stimulated significant progesterone synthesis in female astrocytes (p < 0.05 vs. control). Conversely, male astrocytes did not synthesize progesterone (p > 0.05 vs. controls) when stimulated by estradiol at 1 nM or 100 nM. *Significantly different compared to female control and all male groups (p < 0.05, one-way ANOVA with Student–Newman–Keuls post hoc test). ^†Significantly different compared to female astrocytes stimulated with 1 nM estradiol (p < 0.05, one-way ANOVA with Student–Newman–Keuls post hoc test).

This Figure was originally published by BioMed Central and is reproduced from: Kuo et al. [138]. Biology of Sex Differences adheres to the BioMed Central Open Access license agreement.