. 2012 Oct 17;7(10):e47739. doi: 10.1371/journal.pone.0047739

Table 4. P-values for significance of difference in sample size estimates (Table 3, Figure 3) from pairs of enrichment specifications (rows) for particular measures (columns).

Enrichments	CDR	Brain	Hipp	Amyg	Erc
All vs. Aβ⁺	0.089	0.45	0.097	0.088	0.081
All vs. Aβ⁺Ptau⁺	0.064	0.33	0.057	0.012	0.007
All vs. MRI⁺	0.015	0.12	7×10⁻⁴	5×10⁻⁴	3×10⁻⁵
All vs. MRI⁺Aβ⁺	0.021	0.088	9×10⁻⁴	8×10⁻⁴	6×10⁻⁶
All vs. MRI⁺Aβ⁺Ptau⁺	0.018	0.081	0.003	3×10⁻⁴	<10⁻⁶
Aβ⁺ vs. Aβ⁺Ptau⁺	0.83	0.83	0.78	0.42	0.36
Aβ⁺ vs. MRI⁺	0.58	0.5	0.15	0.13	0.037
Aβ⁺ vs. MRI⁺Aβ⁺	0.41	0.33	0.074	0.071	0.005
Aβ⁺ vs. MRI⁺Aβ⁺Ptau⁺	0.34	0.31	0.12	0.038	0.002
Aβ⁺Ptau⁺ vs. MRI⁺	0.75	0.67	0.27	0.53	0.28
Aβ⁺Ptau⁺ vs. MRI⁺Aβ⁺	0.53	0.45	0.13	0.29	0.051
Aβ⁺Ptau⁺ vs. MRI⁺Aβ⁺Ptau⁺	0.45	0.42	0.19	0.18	0.019
MRI⁺ vs. MRI⁺Aβ⁺	0.7	0.69	0.55	0.58	0.29
MRI⁺ vs. MRI⁺Aβ⁺Ptau⁺	0.61	0.64	0.69	0.38	0.13
MRI⁺Aβ⁺ vs. MRI⁺Aβ⁺Ptau⁺	0.9	0.95	0.87	0.76	0.67

Values significant at the 5% level are underlined and bold. See Table 3 legend for key. Amyg = Amygdala; Erc = entorhinal cortex. Calculation of p-values described in [50].