Table 5. Univariate and multivariates regression analysis for recurrent stroke at 1 year in relation to anti-depressant drugs in patients with PSD.

Model	OR	95%CI
Unadjusted	1.78	0.88–3.57
Adjusted
Model 1*	1.81	0.89–3.68
Model 2†	1.96	0.95–4.04

PSD indicates poststroke depression.

^*: Adjusted by gender and age.

^†: Adjusted by age, gender, traditional risk factors for recurrent stroke (including hypertension, diabetes, hyperlipidemia, smoking, high alcohol consumption, personal history stroke, history cardiovascular disease). And other covariates (including gender, history cardiac disease, NIHSS at admission, ischemic stroke, anti-platelet, lower lipid drug, anti-depressant drugs).

There were 481 cases of PSD at 2 weeks and 66 cases received anti-depressant drugs, among which there were 12 cases of cumulative recurrent stroke at 1 year. Among 415 cases who didn't receive anti-depressant drugs, there were 46 cases of cumulative recurrent stroke at 1 year.