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. 2012 Oct 17;7(10):e47042. doi: 10.1371/journal.pone.0047042

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© 2012 Kumar, Jha

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Ten paired conditioned (tone: 2200 Hz, 90 dB) and unconditioned (foot-shock: 0.8 mA AC current) stimuli were presented over a period of 1200 sec for fear conditioning. Tones were presented at an interval of 60 sec for 5 sec which co-terminated with 1 sec foot-shock. (B) Animals were tested for cued fear-conditioning the next day, during which only conditioned stimulus (tone) of similar sequence, duration and number (as used during cued fear-conditioned (CuFC) training) was presented.