Table 3.

Hazard ratio (95% CI) for one standard deviation decrease in vBMD and cortical thickness (adjusted for age, BMI and study site)

	Infero-medial Femoral Neck	Medial Intertrochanter	Medial Trochanter
Cortical vBMD	1.98 (1.26, 3.10)	2.28 (1.44, 3.63)	2.01 (1.26, 3.20)
	p=0.0030	p=0.0005	p=0.0034
Trabecular vBMD	4.65 (2.64, 8.20)	2.33 (1.27, 4.26)	6.91 (3.11, 15.35)
	p<0.0001	p=0.0060	p<0.0001
Integral vBMD	2.83 (1.71, 4.67)	2.17 (1.34, 3.53)	3.70 (2.04, 6.71)
	p<0.0001	p=0.0017	p<0.0001
Cortical thickness	2.89 (1.65, 5.05)	3.18 (1.74, 5.81)	3.44 (1.70, 6.98)
	p=0.0002	p=0.0002	p=0.0006
	Supero-lateral Femoral Neck	Lateral Intertrochanter	Lateral Trochanter
Cortical vBMD	2.87 (1.55, 5.30)	3.45 (1.90, 6.26)	2.60 (1.44, 4.70)
	p=0.0008	p<0.0001	p=0.0015
Trabecular vBMD	5.45 (2.85, 10.44)	2.80 (1.61, 4.84)	1.00 (0.64, 1.55)
	p<0.0001	p=0.0002	p=0.9874
Integral vBMD	3.90 (2.12, 7.16)	2.71 (1.56, 4.71)	1.86 (0.96, 3.60)
	p<0.0001	p=0.0004	p=0.0651
Cortical thickness	5.13 (1.91, 13.72)	3.68 (1.77, 7.66)	2.60(1.54, 4.38)
	p=0.0011	p=0.0005	p=0.0004
	Femoral Neck	Intertrochanter	Trochanter	Total hip
Cortical vBMD	2.36 (1.46, 3.82)	3.09 (1.80, 5.30)	2.45 (1.45, 4.12)	2.61 (1.60, 4.27)
	p=0.0005	p<0.0001	p=0.0008	p=0.0001
Trabecular vBMD	6.54 (3.35, 12.77)	4.02 (2.01, 8.05)	2.74 (1.43, 5.29)	4.92 (2.55, 9.50)
	p<0.0001	P<0.0001	p=0.0025	p<0.0001
Integral vBMD	3.34 (1.95, 5.71)	2.86 (1.68, 4.86)	3.53 (1.87, 6.67)	3.23 (1.82, 5.72)
	p<0.0001	p=0.0001	p=0.0001	p<0.0001
Cortical thickness	3.49 (1.82, 6.71)	3.67 (1.86, 7.25)	3.09 (1.69, 5.66)	2.54 (1.59, 4.05)
	p=0.0002	p=0.0002	p=0.0003	p<0.0001
Cross section area	1.10 (0.76, 1.58)	1.07 (0.65, 1.74)	1.05 (0.65, 1.70)
	p=0.6260	p=0.7901	p=0.8373
PMI	2.73 (1.43, 5.20)	2.35 (1.27, 4.33)	1.45 (0.94, 2.23)
	p=0.0022	p=0.0063	p=0.0958

PMI: Polar moment of inertia.