Table 1.

Relation Between Insulin Sensitivity (S_I)^* and Glucose Effectiveness (S_G)

	Control Subjects	Type 2 Diabetics	P	Ref.
SG(min-1)	0.023 ± 0.002			[2]
	0.016 ± 0.001	0.010 ± 0.001	<0.01	[12]
	0.020 ± 0.002	0.013 ± 0.001	<0.05	[13]
	0.023 ± 0.012	0.016 ± 0.009	<0.0001	[14†]
SI(×10-4·min-1·mU-1·L)	5.61 ± 0.51			[2]
	11.8 ± 2.6	6.7 ± 0.8	<0.05	[13]
	13.45 ± 11.12	5.31 ± 3.98	<0.0001	[14†]

^*We used the conversion factor: 1 mU/L = 6.00 pmol/L;

^†more than 10 years before the development of diabetes