Table 2.
Chronic dopamine depletion increases the maximum evoked GABAA receptor-mediated synaptic conductance but has no effect on short-term synaptic plasticity
| Control (nS) | 6-OHDA (nS) | Significance | |
|---|---|---|---|
| IPSC1 | 7.03 ± 3.10 (n = 20) | 11.17 ± 5.41 (n = 15) | p < 0.05 |
| IPSC25 (10 Hz) | 5.59 ± 2.58 (n = 20) | 8.62 ± 4.42 (n = 15) | p < 0.05 |
| IPSC2:IPSC1 (10 Hz) | 0.94 ± 0.06 (n = 20) | 0.96 ± 0.04 (n = 15) | NS |
| IPSC25:IPSC1 (10 Hz) | 0.79 ± 0.10 (n = 20) | 0.77 ± 0.09 (n = 15) | NS |
| IPSC2:IPSC1 (50 Hz) | 0.86 ± 0.18 (n = 20) | 0.89 ± 0.16 (n = 14) | NS |
| IPSC25:IPSC1 (50 Hz) | 0.56 ± 0.18 (n = 20) | 0.64 ± 0.21 (n = 14) | NS |
The frequency of electrical stimulation (10 or 50 Hz) and the number of the evoked IPSC (e.g., IPSC1 and IPSC2) are denoted.