Table 2.
CYP1B1 induction (fold-change measured by RT-PCR) in NHMEC strains by BP in the absence (T1a) and presence (T2, T3, T4) of chlorophyllin.
| Cell Strain | T1a | T2 | T3 | T4 |
|---|---|---|---|---|
| M98014 | 3.5 ± 0.6b | 2.9 ± 0.9 | 7.9 ± 1.0 | 6.8 ± 1.8 |
| M98015 | 43.4 ± 4.8 | 35.9 ± 3.3 | 39.7 ± 9.3 | 39.3 ± 6.9 |
| M98011 | 4.7 ± 0.9 | 3.7 ± 1.5 | 5.7 ± 1.5 | 6.3 ± 1.5 |
| M99003 | 19.7 ± 1.9 | 13.0 ± 1.2 | 15.3 ± 1.0 | 16.5 ± 5.2 |
| M99015 | 33.9 ± 1.7 | 13.5 ± 2.3 | 22.6 ± 11.2 | 19.9 ± 3.7 |
| M98019 | 6.1 ± 0.4 | 4.4 ± 0.4 | 7.9 ± 1.0 | 6.8 ± 1.8 |
| M98025 | 8.4 ± 2.2 | 4.4 ± 1.8 | 4.8 ± 1.5 | 3.9 ± 0.5 |
| M99021 | 8.8 ± 1.4 | 5.8 ± 1.0 | 6.3 ± 1.2 | 5.5 ± 0.9 |
| M00012 | 17.5 ± 3.1 | 10.3 ± 1.7 | 14.6 ± 4.4 | 11.9 ± 3.3 |
| M98026 | 31.7 ± 3.3 | 21.1 ± 1.7 | 24.2 ± 8.4 | 23.6 ± 6.4 |
| M99004 | 12.1 ± 1.3 | 7.7 ± 1.3 | 7.0 ± 0.7 | 6.9 ± 0.8 |
| M99016 | 8.9 ± 1.4 | 8.6 ± 1.6 | 8.3 ± 1.1 | 6.9 ± 1.3 |
| M99006 | 8.9 ± 1.6 | 5.5 ± 0.4 | 9.9 ± 3.6 | 4.8 ± 0.8 |
| M00004 | 7.9 ± 2.6 | 5.1 ± 0.5 | 7.3 ± 2.9 | 4.5 ± 2.0 |
| M98035 | 9.5 ± 1.9 | 8.0 ± 1.8 | 7.3 ± 1.8 | 3.3 ± 0.4 |
| M98030 | 16.0 ± 4.1 | 7.0 ± 1.4 | 6.5 ± 1.0 | 4.9 ± 1.8 |
| M99005 | 9.2 ± 1.8 | 7.5 ± 0.4 | 5.8 ± 1.7 | 3.5 ± 1.3 |
| M99025 | 22.9 ± 3.9 | 11.4 ± 3.1 | 9.2 ± 1.2 | 6.5 ± 1.3 |
| M98016 | 14.7 ± 3.0 | 6.2 ± 0.6 | 10.0 ± 5.9 | 3.9 ± 1.1 |
| M98013 | 42.0 ± 6.9 | 14.0 ± 1.5 | 11.5 ± 1.9 | 7.0 ± 3.2 |
a
T = Treatment groups as defined in Section 2.
b
Numbers represent fold-change ±SD (n = 2).