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. Author manuscript; available in PMC: 2012 Oct 18.
Published in final edited form as: Adv Exp Med Biol. 2012;726:423–439. doi: 10.1007/978-1-4614-0980-9_19

Figure 8. Snapshots of the herpesvirus life cycle.

Figure 8

(A) Nuclear egress. Tomographic slice from a vitrified section of a NIH 3T3 cell infected with murine cytomegalovirus (for preparation details, see Scrivano et al. 2010). Inside the nucleus are seen a B-capsid and a C-capsid budding into the inner nuclear membrane. A layer of density between them (arrow) is likely to represent a layer of protein. Courtesy of Drs C. Hagen and K. Grünewald. (B) Cell entry. Slice from a tomogram of a PtK2 cell, where two capsids of recently entered HSV-1 virions are visible. The strip of density along the cell membrane (arrow) appears to represent divested tegument. From (Maurer et al. 2008), courtesy of Dr. K. Grünewald. Bar, 100 nm.