Table 3.
Changes in some sneeze-related variables recorded ~10 min following bilateral microinjections of 1 mM Bicuculline, 0.3 Muscimol, and vehicle solution into the cVRG.
SN | PPA, RU | PAA, RU | |
---|---|---|---|
BICUCULLINE (n = 5) | |||
Control | 3.4 ± 0.25 | 0.72 ± 0.04 | 0.44 ± 0.05 |
1 mM | 4.8 ± 0.22* | 0.66 ± 0.03 | 0.49 ± 0.06* |
MUSCIMOL (n = 5) | |||
Control | 3.8 ± 0.32 | 0.67 ± 0.03 | 0.46 ± 0.02 |
0.3 mM | – | 0.63 ± 0.02 | – |
VEHICLE SOLUTION (n = 3) | |||
Control | 3.5 ± 0.31 | 0.68 ± 0.04 | 0.45 ± 0.05 |
0.9% NaCl | 3.4 ± 0.28 | 0.69 ± 0.04 | 0.47 ± 0.04 |
Values are means ± SE; n, number of animals; cVRG, caudal ventral respiratory group; SN, sneeze number; PPA, peak phrenic activity in relative units (RU); PAA, peak abdominal activity in relative units (RU); −, sneeze response absent or barely visible (non-measurable).
P < 0.05 compared with control sneeze.