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. 2012 Jun 8;18(1):1086–1095. doi: 10.2119/molmed.2012.00033

Figure 2.

Figure 2

R-roscovitine reduces PMNs and total protein levels in LTA-induced lung inflammation. Lung inflammation was induced by intranasal instillation of 100 μg LTA. Simultaneously, 70 mg/kg R-roscovitine or vehicle (0.05% DMSO) was administered intraperitoneally. After 6 and 24 h, samples were harvested. Cell differentiations (A) and PMN numbers (B) were determined on Giemsa-stained cytospin preparations derived from BAL fluid. Total protein (C) levels were measured in BAL fluid. Data are expressed as mean ± SEM; n = 8. *P < 0.05; **P < 0.01, ***P < 0.001.