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Residues involved in the first three PSE-4 normal modes in the free and ligand-bound enzyme. FF: free form; BF: bound form; V: eigenvector number. Residues are colored on a scale from blue to red according to their amplitude of motion within the eigenvector; blue means little amplitude and red high amplitude. The Ω loop and helices H2 and H3 are indicated in the first panel.
