Figure 8.

Effects of the presence of 0.25 mm La³⁺ on 5 μm Ag⁺-induced (A and B) and 0.2 mm NEM-induced (C and D) membrane depolarization. Note that in C, La³⁺ was added after NEM addition, so that NEM-induced depolarization had already reached its maximum (about 15 min) but ΔQO₂ had not yet started (compare Fig. 7). Data are from one representative experiment out of three. A, Depolarization by 5 μm Ag⁺; B, its inhibition by La³⁺; C, depolarization by 0.2 mm NEM and its reversal by La³⁺; and D, inhibition by the presence of La³⁺ of the NEM-induced depolarization.