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. 2012 Aug 29;32(35):12051–12065. doi: 10.1523/JNEUROSCI.1857-12.2012

Figure 1.

Figure 1.

Reelin overexpression leads to faster development of the dendritic tree of adult-generated neurons. A, Experimental design. Eight-week-old mice were injected with GFP-expressing retrovirus and killed at several time points after surgery. B, Representative images of GFP-labeled adult-born neurons at 2, 4, and 8 weeks after injection in WT and Reelin-OE mice. C–E, Quantification of morphological parameters of adult-generated neurons in WT and Reelin-OE mice at several time points after surgery. C, The number of primary dendrites was similar between groups. D, The number of branches in adult-generated neurons of Reelin-OE mice at 2 weeks after surgery was higher than in WT mice (t test: p < 0.05). E, The dendritic length in adult-generated neurons of Reelin-OE mice at 2 weeks after surgery was higher than in WT mice (t test: p < 0.05). F, Distance from the SGZ was greater in Reelin-OE mice at 2 weeks after injection (t test: p < 0.05). G, H, Sholl analysis shows fewer intersections in 2-week-old adult-generated neurons in WT than in Reelin-OE mice (t test: p < 0.05).