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. Author manuscript; available in PMC: 2013 Oct 3.
Published in final edited form as: Cell Metab. 2012 Oct 3;16(4):487–499. doi: 10.1016/j.cmet.2012.09.004

Figure 5.

Figure 5

Effects of XBP1 ablation in dyslipidemic mouse models. (A) Metabolic parameters of 8-week old Xbp1f/f;ob/ob and Xbp1LKO;ob/ob mice measured after a 4-h fasting. n = 4–6 female mice per group. (B) Hepatic mRNA levels were measured by qRT-PCR. (C) WT and Xbp1Δ mice were fed a high fat diet for 5 months, and then sacrificed to measure metabolic parameters. n = 9–10 male mice per group. Values represent mean ± SEM. *P <0.05, **P <0.01, ***P <0.001.