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. Author manuscript; available in PMC: 2012 Oct 18.
Published in final edited form as: Drug Dev Res. 1996 Sep 1;39(1):36–46. doi: 10.1002/(sici)1098-2299(19960901)39:1<36::aid-ddr5>3.0.co;2-l

Figure 3.

Figure 3

Inhibition by MRS 1067 of phosphoinositide breakdown elicited by NECA and 2-CI-IBMECA in RBL-2H3 mast cells. Accumulation of [3H]inositol phosphates was measured as described in METHODS with NECA (10 µM) or 2-CI-IBMECA (10 µM) either alone or with MRS 1067 (30 µM). Incubations were for 1 min in cells pretreated overnight with DNP-specific IGE and then challenged with the antigen DNP-HSA. Values are means ± s.e.m. (n = 3). *p <0.05.