Table 4.
Average number of individuals in the augmented data set who follow the static regime, AA, always treat with an atypical antipsychotic and the each of the perphenazine and atypical regimes, PA(θ), for the entire 12 months. Recall, the regime PA(30) corresponds to a static regime of always treat with perphenazine. Note all numbers in this table are averaged over the 25 imputations used to overcome missing data in the original, non bootstrapped data set, where missing data arose from both item missingness and study attrition. Additionally, we present each data summary by baseline treatment assignment, perphenazine or an atypical, as well as the total number. The first three columns correspond to the individuals who can contribute information for each regime, i.e. the number of replicates who start following each regime; this includes individuals who may be artificially censored for subsequent assignment to clozapine, ziprasidone or for entering into the unrandomized, unblinded phase of CATIE. The second three columns are the number of replicates who were not censored for going off their assigned treatment regime; these individuals could have been censored for subsequent assignment to clozapine, ziprasidone or for entering into the unrandomized, unblinded phase of CATIE. The last three columns are the number of replicates included in the final analysis, this excludes all individuals artificially censored for no longer following their assigned treatment regime, as well as all replicated who were censored because their corresponding individuals were subsequently assigned to clozapine, ziprasidone or entered into the unrandomized, unblinded phase of CATIE.
| Treatment regime |
N who started on each regime | N who were not artificially censored | N included in final analysis | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline Trt | Total | Baseline Trt | Total | Baseline Trt | Total | ||||
| Perp | Atypical | All | Perp | Atypical | All | Perp | Atypical | All | |
| AA | NA | 815.0 | 815.0 | NA | 815.0 | 815.0 | NA | 380.4 | 380.4 |
| PA(θ = 30) | 261.0 | NA | 261.0 | 81.0 | NA | 81.0 | 81.0 | NA | 81.0 |
| PA(θ = 35) | 259.0 | 3.0 | 262.0 | 76.5 | 3.0 | 79.5 | 73.5 | 1.0 | 74.5 |
| PA(θ = 40) | 255.0 | 8.0 | 263.0 | 79.3 | 8.0 | 87.3 | 71.1 | 5.0 | 76.2 |
| PA(θ = 45) | 247.9 | 24.2 | 272.1 | 86.6 | 24.2 | 90.8 | 61.9 | 14.6 | 76.5 |
| PA(θ = 50) | 240.9 | 46.4 | 287.3 | 94.6 | 46.4 | 101.0 | 47.2 | 27.6 | 74.9 |
| PA(θ = 55) | 224.8 | 83.8 | 308.6 | 123.6 | 83.8 | 207.4 | 38.8 | 49.2 | 88.1 |
| PA(θ = 60) | 207.8 | 132.4 | 340.1 | 163.2 | 132.4 | 295.5 | 30.1 | 72.3 | 102.4 |
| PA(θ = 65) | 183.6 | 208.0 | 391.7 | 234.8 | 208.0 | 442.8 | 25.4 | 105.4 | 130.7 |
| PA(θ = 70) | 156.6 | 290.5 | 447.1 | 311.3 | 290.5 | 601.8 | 19.4 | 145.5 | 164.9 |