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(A) Full-length procaspase-3 (32 kD) and cleaved fragments (21 kD and 12 kD) were detected in the samples from the temporal cortex. These cleaved forms were little found in the nonpathologic control (NPC) brains. (B) Caspase-3 activity in mitochondria was elevated in mitochondria of PD brains compared to NPC samples (ap < 0.05).
