Table 3. Multivariate logistic regression to ascertain variables associated with “cure” (i.e. to become egg-negative after treatment) in 282 children (5 months–7 year olds).
Variable | Baseline category | Test category | OR (CI95) | P-value |
Age | 1–3 year olds | 4–7 year olds | 3.53 | <0.001 |
(1.75–7.12) | ||||
Sex | Boy | Girl | 0.70 | 0.22 |
(0.40–1.23) | ||||
Dosage of praziquantel received at baseline | 34.6 mg/Kg* | +1 mg/Kg | 0.96 | 0.49 |
(0.85–1.08) | ||||
No. treatment rounds in the past 18 months | Never been treated | One round | 0.35 | 0.003 |
(0.17–0.71) | ||||
Two rounds | 0.06 | <0.00001 | ||
(0.03–0.15) | ||||
Three or more rounds | 0.08 | <0.00001 | ||
(0.04–0.20) | ||||
Daily time in water | 0 hours | +1 category | 0.85 | 0.24 |
(0.65–1.11) | ||||
Was infection at baseline >399 epg (heavy)? | No | Yes | 0.47 | 0.028 |
(0.24–0.92) |
Time in water categories: 0 = zero hours, 1 = <30 min, 2 = 30–60 min, 3 = 60–120 min, 4 = >120 min.
34.6 mg/Kg was the minimum dosage given in our survey population, while the maximum dosage was 45.1 mg/Kg.