Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Oct 18;8(10):e1002746. doi: 10.1371/journal.pcbi.1002746

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 Birch et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Dynamic time courses of experimental host population data uninfected (line is mean of n = 2) and infected cultures (line is mean of n = 3); an immediate drop in population density occurs when the solution of phage is added at , due to dilution. Initial infection multiplicity was 0.1. (B) Measured and simulated phage production per infected host in tryptone broth media (circles are mean, error bars shown are the standard deviation, n = 3). Simulation presented for the integrated model and T7 ODEs alone simulated at . (C) Expanded comparison of the simulated concentrations of critical phage replication machinery and phage virion components compared to T7 ODEs alone. Gene Product 1 is the T7 RNA polymerase; Gene product 10A is the major capsid protein.

Inline graphic — (A) Dynamic time courses of experimental host population data uninfected (line is mean of n = 2) and infected cultures (line is mean of n = 3); an immediate drop in population density occurs when the solution of phage is added at , due to dilution. Initial infection multiplicity was 0.1. (B) Measured and simulated phage production per infected host in tryptone broth media (circles are mean, error bars shown are the standard deviation, n = 3). Simulation presented for the integrated model and T7 ODEs alone simulated at . (C) Expanded comparison of the simulated concentrations of critical phage replication machinery and phage virion components compared to T7 ODEs alone. Gene Product 1 is the T7 RNA polymerase; Gene product 10A is the major capsid protein.