Figure 8. Proliferation is required for regeneration after treatment with cisplatin.

(A) Wild type larvae were treated at 5 dpf with 50 μM cisplatin for 24 h and allowed to recover for 72 h (96 h from the beginning of treatment). Regeneration was considerable yet remained incomplete. (B) When fish were incubated in flubendazole during recovery, minimal regeneration was observed, suggesting that proliferation was required. N = 8 fish per group. Error bars are +/− SD.