Table 1. Summary of DAPPLE analysis of significant and significant plus suggestive SNPs.
Significant | Significance | Significant + suggestive | Significance | |
Number of proteins in the network | 75 | - | 189 | - |
Direct interactions | 104 | p<0.0002 | 281 | p<0.007 |
MAPDC * | 2.7 | p<0.0002 | 2.9 | p = 0.0008 |
MAPIC ** | 52.2 | p = 0.04 | 93 | p = 0.34 |
Mean CI connectivity *** | 4.5 | p = 0.0002 | 5.05 | p = 0.05 |
Genes to prioritize | 39 | - | 22 | - |
Mean associated protein direct connectivity;
Mean associated protein indirect connectivity;
Mean Common Interactor connectivity.