Figure 2. Pro-ANP processing activity in Tg mouse hearts.
(A–D) Pro-ANP processing activity was assayed using membrane fractions from corin WT, KO, KO/TgWT and KO/TgV mouse hearts. Conversion of pro-ANP to ANP was analyzed by immunoprecipitation and Western blotting. (E) Quantitative data of Western blots from 3 independent experiments.