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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Aug 23;32(11):2702–2710. doi: 10.1161/ATVBAHA.112.300115

Figure 3. Reduced Krit1 expression directly alters microvessel permeability.

Figure 3

A) Permeability of albumin in arterioles of Krit1+/− and Krit1+/+ mice. Data shown is mean Ps +/− SEM, Overall p<0.0001 by ANOVA. B) Permeability of albumin in venules of Krit1+/− and Krit1+/+ mice. Overall p<0.001 by ANOVA. C) Relative ICAM-1 and Krit1 mRNA expression in siRNA-transfected mouse MVEC treated with either TNF–α, or serum isolated from Krit1+/+ (WT) or Krit1+/− mice, or both. NC- negative control siRNA transfected cells, Krit1- anti-Krit1 siRNA transfected cells, n=3.